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Cover of Enough by Oprah Winfrey & Ania M. Jastreboff

Enough

Oprah Winfrey & Ania M. Jastreboff

Published 2026

Jastreboff does the science — obesity as a regulated disease, GLP-1s as treatment — and Oprah does the thirty years of being blamed for it in public. The pairing is the argument: the mechanism and the shame, in the same book. It reframes a conversation most people are still having in the old vocabulary.